Such devices typically consist of a sensor that is applied on the surface of the body to measure glucose concentrations and a transmitter by which the glucose data are displayed. The CGMS can measure the IG concentrations in the subcutaneous interstitial fluid. The use of CGMS has been already described in veterinary medicine, 2- 9 even though the devices used in previous studies have a number of limitations and are not commonly used clinically.
Moreover, the BCGs in the hospital are time consuming and expensive. The main limitations of the BGCs interpretation include the requirement of numerous capillary drops of blood that in some dogs can be difficult to obtain and become a source of stress nevertheless, the glucose nadir or peak can be missed measuring the blood glucose concentration every 2 hours.
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Nowadays, some owners are able to perform home monitoring by measuring the capillary blood glucose concentrations using a portable blood glucose meter (PBGM). To perform a BGC, the diabetic dog is generally hospitalized for 10–12 hours and the capillary blood glucose concentration is usually measured every 2 hours. In diabetic dogs, the evaluation of blood glucose curves (BGCs) allows the clinician to determine if the insulin administered is effective and identify the glucose nadir, time of peak insulin effect, duration of insulin effect, and degree of fluctuation in blood glucose concentrations in that particular dog. Different systems for real-time CGMS have been available for the use in human diabetic patients and many publications support the clinical benefit of the CGMS. Self-monitoring blood glucose system and continuous glucose monitoring systems (CGMS) are routinely used in human diabetic patients. Glycemic control is a cornerstone for the management of diabetes mellitus (DM) in human and veterinary medicine. The FGMS is easy to use and is accurate for IG glucose measurement in diabetic dogs. Mean ± standard deviation difference from the reference method was 2.3 ± 46.8 mg/dL. The FGMS was 93, 99, and 99% accurate at low, normal, and high blood glucose concentrations. A good correlation between IG and PG concentrations (rho = 0.94 P <. Mild erythema at the site of the application was found in 5/10 dogs at the end of the wearing period. The application and the use of the FGMS were apparently painless, easy, and well tolerated by all dogs. During the 1st–2nd, 6–7th, and 13–14th days from application, the IG measurements were compared with the plasma (EDTA) glucose (PG) concentrations analyzed by a reference hexokinase based method. The FGMS was placed on the neck for up to 14 days. Ten client-owned diabetic dogs on insulin treatment. To assess the clinical and analytical accuracy of the FGMS in diabetic dogs. It continuously measures the interstitial glucose (IG) concentrations for 14 days. A novel flash glucose monitoring system (FGMS) (FreeStyle Libre, Abbott, UK) was recently developed for humans.
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